Warhammer 40,000: Kill Team is a top-down, twin-stick shooter set in the future fantasy universe of Warhammer 40,000. Players play as Space Marines attempting to stop an Ork invasion spaceship, facing Orks and later Tyranids. There are four classes of Space Marines: Aft Guard Veteran, Techmarine, Vanguard Veteran and Librarian. The first two are focused on shooting, the last 2 are focused on melee combat. The game supports single-player mode and multiplayer mode on the same screen.