A multiplayer game similar to Buckshot Roulette, in which a pair of gamers undergo medical tests. The subjects take turns taking pills that could be beneficial... Read more
Side Effects News
The latest news and rumors about Side Effects for 2026: release date, trailers, announcements, leaks and system requirements. We follow the game every day on VGTimes.
Side Effects Turns Russian Roulette Into a Deadly Medical Experiment — Free Demo Now on Steam
A new demo for Side Effects — a twisted medical take on Buckshot Roulette — is now available on Steam. The game reimagines the brutal one-on-one format as a high-stakes experiment where two patients take turns swallowing pills, one of which is poisoned. According to the developers, the project also draws inspiration from the management sim Big Pharma.
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October 9, 2025